Ethylenediaminetetraacetic Acid (EDTA) – Dependent Pseudothrombocytopenia: A Case Report

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48, XXYY syndrome associated with ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia.

A 56-yr-old man with hypogonadism, gynecomastia, and mental retardation was evaluated for chromosome constitution and thrombocytopenia. Chromosomal analysis demonstrated the mosaicism of 48, XXYY and 47, XXY in the peripheral lymphocytes. Twenty out of twenty-five cells were 48, XXYY karyotype and the remaining five were 47, XXY karyotype. Thrombocytopenia was the EDTA-dependent pseudothrombocy...

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Poorer Prognosis With Ethylenediaminetetraacetic Acid-dependent Pseudothrombocytopenia

In ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (PTCP), automated platelet counts are lower than actual counts because of EDTA-induced aggregation. Factors contributing to the incidence of EDTA-PTCP are unknown, and no study has assessed the prognosis of EDTA-PTCP patients. This retrospective study assessed characteristics in EDTA-PTCP patients and matched controls to...

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EDTA (Ethylenediaminetetraacetic Acid)

Ethylenediaminetetraacetic acid (EDTA) was developed by Franz Munz inGermanyduring the 1930s as an alternative to citric acid. About the same time, Frederick Bersworth synthesized EDTA in the United States using a different technique. He obtained aUSpatent for this technique in1945. EDTAwas approvedby the US Food and Drug Administration (FDA) as a food additive in 1947. Since the early 1950s, E...

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Poorer prognosis with ethylenediaminetetraacetic acid-dependent pseudothrombocytopenia: a single-center case-control study.

In ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (PTCP), automated platelet counts are lower than actual counts because of EDTA-induced aggregation. Factors contributing to the incidence of EDTA-PTCP are unknown, and no study has assessed the prognosis of EDTA-PTCP patients. This retrospective study assessed characteristics in EDTA-PTCP patients and matched controls to...

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EDTA Dependent Pseudothrombocytopenia In A Patient With Scrub Typhus - A Case Report

We report a case of EDTA induced pseudothrombocytopenia (EDTA-PTCP) in a patient with scrub typhus who was referred as a case of pyrexia of unknown origin (PUO) with marked thrombocytopenia and treated with platelet transfusion. Blood smear examination revealed numerous platelet aggregates. CBC analysis using citrate and lithium-heparin as anticoagulants as well as a peculiar WBC histogram aide...

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ژورنال

عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

سال: 2014

ISSN: 2249-782X

DOI: 10.7860/jcdr/2014/9603.5019